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15 changes: 15 additions & 0 deletions .gitignore
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CLAUDE.md

# macOS resource forks and metadata
.DS_Store
._.DS_Store
._*

# vignette build artifacts (rendered HTMLs in vignettes/ dir)
vignettes/*.html

# Claude Code internal directory
.claude/

# scratch / legacy
old/
3 changes: 2 additions & 1 deletion DESCRIPTION
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@@ -1,6 +1,6 @@
Package: compact
Title: compact
Version: 0.0.3
Version: 0.1.0
Authors@R: c(
person("Sam", "Morabito", , "smorabit@uci.edu", role = c("aut", "cre"),
comment = c(ORCID = "0000-0002-7768-4856")),
Expand Down Expand Up @@ -28,6 +28,7 @@ Imports:
xgboost (>= 1.7.11.1),
SHAPforxgboost (>= 0.1.3),
ggplot2,
ggrepel,
data.table,
ggrastr,
pbapply,
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19 changes: 19 additions & 0 deletions NAMESPACE
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Expand Up @@ -16,11 +16,15 @@ export(FindShapKeyDriver)
export(HeatmapDistance)
export(LoadAlertSystem)
export(LoadAlertSystemPathways)
export(MacrostateTransitions)
export(ModelZINB)
export(ModulePerturbation)
export(PerturbationLog2FC)
export(PerturbationTransitions)
export(PerturbationVectors)
export(PlotMacrostateTransitions)
export(PlotMarkovEmbedding)
export(PlotMarkovScatter)
export(PlotTransitionVectors)
export(PredictAttractors)
export(PredictCommitment)
Expand Down Expand Up @@ -52,13 +56,28 @@ importFrom(dplyr,rename)
importFrom(ggplot2,aes)
importFrom(ggplot2,coord_fixed)
importFrom(ggplot2,element_blank)
importFrom(ggplot2,element_line)
importFrom(ggplot2,element_rect)
importFrom(ggplot2,element_text)
importFrom(ggplot2,geom_hline)
importFrom(ggplot2,geom_point)
importFrom(ggplot2,geom_smooth)
importFrom(ggplot2,geom_text)
importFrom(ggplot2,geom_tile)
importFrom(ggplot2,geom_vline)
importFrom(ggplot2,ggplot)
importFrom(ggplot2,ggtitle)
importFrom(ggplot2,labs)
importFrom(ggplot2,scale_color_discrete)
importFrom(ggplot2,scale_color_gradientn)
importFrom(ggplot2,scale_color_manual)
importFrom(ggplot2,scale_fill_gradientn)
importFrom(ggplot2,scale_x_discrete)
importFrom(ggplot2,scale_y_discrete)
importFrom(ggplot2,theme)
importFrom(ggplot2,theme_bw)
importFrom(ggplot2,theme_minimal)
importFrom(ggrepel,geom_label_repel)
importFrom(igraph,components)
importFrom(igraph,graph_from_adjacency_matrix)
importFrom(methods,as)
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11 changes: 11 additions & 0 deletions NEWS.md
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@@ -1,3 +1,14 @@
# 0.1.0 (05-20-2026)
## Added
- `MacrostateTransitions` and `PlotMacrostateTransitions`: coarse-grain the cell-level transition probability matrix into a K × K group-level summary, with a stability index on the diagonal and a heatmap visualization.
- `CombinePerturbAssays`: combine multiple perturbation assays by additive delta superposition into a single composite assay.
- New vignette: **Basics — Simulated Branching Trajectory** (`simulation_tutorial`) covering the full `ModulePerturbation` workflow, graph connectivity checks, expression inspection, vector fields, macrostate transitions, and Markov chain analyses.
- New vignette: **Advanced Use Cases — NSCLC CD8+ T Cells** (`advanced_NSCLC`) demonstrating step-by-step use of `ApplyPerturbation`, `ApplyPropagation`, and `PerturbationTransitions` with a custom gene set, a pseudobulk Pearson correlation network, `CustomPerturbation`, and `CombinePerturbAssays`.
- pkgdown documentation site updated with both new vignettes.

## Changes
- None

# 0.0.3 (02-20-2025)
## Added
- New functions for cell fate analysis: `PredictPerturbationTime`, `PredictAttractors`, `PredictFates`, and `PredictCommitment`.
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