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mentatpsi/README.md

Hi, I'm Shay Maor (@mentatpsi)

Software Engineer and hobbyist Computational Biologist building at the intersection of genomics, bioinformatics, and health AI.

About Me

  • ๐Ÿงฌ Author of OSGenome and OSGenome v2 : a genomic analysis framework for 23andMe SNP data, featured in Harvard Medical School's BioGrids registry (v1)
  • ๐Ÿ“„ Co-author of two peer-reviewed Application Notes in Oxford Bioinformatics
  • ๐ŸŽ“ BS Computer Science (Minor: Psychology) ยท MS Software Development
  • ๐Ÿ“š Currently completing Stanford School of Medicine's AI in Healthcare specialization on Coursera
  • ๐Ÿฅ Focused on applying AI and machine learning to clinical and genomic data

What I'm Working On

  • Extending OSGenome with local AI integration for privacy-first genomic interpretation
  • Exploring ML applications in computational biology and clinical genomics
  • Building at the intersection of bioinformatics and modern AI tooling

Tech Stack

Languages:    Python, C#, Java
Bioinformatics: SNP analysis, genomic data pipelines
ML/AI:        scikit-learn, numpy, llama-cpp-python, HuggingFace
Tools:        Git, Visual Studio, Visual Studio Code

Publications

  • MOST โ€“ Visualization: Software for producing automated textbook-style maps of genome-scale metabolic networks Co-Author April 2017 Bioinformatics, Oxford Journals Visualization of metabolites, reactions and pathways in genome-scale metabolic networks (GEMs) can assist in understanding cellular metabolism. Three attributes are desirable in software used for visualizing GEMs: 1. automation, since GEMs can be quite large; 2. production of understandable maps that provide ease in identification of pathways, reactions, and metabolites; and 3. visualization of the entire network to show how pathways are interconnected. No software currently exists for visualizing GEMs that satisfies all three characteristics, but MOST-Visualization, an extension of the software package MOST (Metabolic Optimization and Simulation Tool), satisfies (1), and by using a pre-drawn overview map of metabolism based on the Roche map satisfies (2) and comes close to satisfying (3).

  • MOST: A software environment for constraint-based metabolic modeling and strain design Co-Author October 14, 2014 Bioinformatics, Oxford Journals MOST (Metabolic Optimization and Simulation Tool) is a software package that implements GDBB (Genetic Design through Branch and Bound) in an intuitive user-friendly interface with Excel-like editing functionality, as well as implementing FBA (Flux Balance Analysis), and supporting SBML (Systems Biology Markup Language) and CSV (Comma-Separated Values) files. GDBB is currently the fastest algorithm for finding gene knockouts predicted by FBA to increase production of desired products, but GDBB has only been available on a command line interface, which is difficult to use for those without programming knowledge, until the release of MOST.

Connect

Pinned Loading

  1. Microchip Microchip Public

    Microchip's PIC MCU Library

    C 117 147

  2. OSGenome OSGenome Public

    An Open Source Web Application for Genetic Data (SNPs) using 23AndMe and Data Crawling Technologies

    Python 145 18

  3. KEGG-Crawler KEGG-Crawler Public

    A parallel API crawler for the retrieval of Kyoto Encyclopedia of Genes and Genomes metabolic and genomics data.

    Python 23 4

  4. OSGenome2 OSGenome2 Public

    An Open Source Web Application for Genetic Data (SNPs) using 23AndMe and Data Crawling Technologies

    HTML 14 4

  5. MOST MOST Public

    Forked from dennisegen/MOST

    MOST - Metabolic Optimization and Simulation Tool (Save Functionality into SBML)

    Java 2

  6. RandomizedCancerGenomics RandomizedCancerGenomics Public

    An implementation of Machine Learning and Data Science on a Breast Cancer study from Memorial Sloan Kettering Cancer Center from 2018. All data was made available on cBioPortal.

    Jupyter Notebook 2