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Baskerville

Sequential regulatory activity predictions with deep convolutional neural networks.

Baskerville provides researchers with tools to:

  1. Train deep convolutional neural networks to predict regulatory activity along very long chromosome-scale DNA sequences
  2. Score variants according to their predicted influence on regulatory activity across the sequence and/or for specific genes.
  3. Annotate the specific nucleotides that drive regulatory element function.

Documentations

Documentation page: https://calico.github.io/baskerville/index.html


Installation

git clone git@github.com:calico/baskerville.git cd baskerville pip install .


Contacts

Dave Kelley (codeowner)

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Machine learning methods for DNA sequence analysis (Yeast / LLM fork).

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