diff --git a/packages/pyright-internal/src/analyzer/typeGuards.ts b/packages/pyright-internal/src/analyzer/typeGuards.ts
index 82f2353e0f72..d4e3a2e6ea68 100644
--- a/packages/pyright-internal/src/analyzer/typeGuards.ts
+++ b/packages/pyright-internal/src/analyzer/typeGuards.ts
@@ -2137,8 +2137,11 @@ function narrowTypeForContainerType(
         return referenceType;
     }
 
-    // Determine which tuple types can be eliminated. Only "None" and
-    // literal types can be handled here.
+    // Determine which tuple types can be eliminated. Only "None",
+    // literal types, and final instantiable classes can be handled here.
+    // Non-final instantiable classes (type[A]) cannot be eliminated in negative
+    // tests because a subclass SubA(A) reaches the negative branch at runtime
+    // (since SubA != A).
     const typesToEliminate: Type[] = [];
     containerType.priv.tupleTypeArgs.forEach((tupleEntry) => {
         if (!tupleEntry.isUnbounded) {
@@ -2146,6 +2149,8 @@ function narrowTypeForContainerType(
                 typesToEliminate.push(tupleEntry.type);
             } else if (isClassInstance(tupleEntry.type) && isLiteralType(tupleEntry.type)) {
                 typesToEliminate.push(tupleEntry.type);
+            } else if (isInstantiableClass(tupleEntry.type) && ClassType.isFinal(tupleEntry.type)) {
+                typesToEliminate.push(tupleEntry.type);
             }
         }
     });
diff --git a/packages/pyright-internal/src/tests/checker.test.ts b/packages/pyright-internal/src/tests/checker.test.ts
index 75c25ecc617b..b77f31987886 100644
--- a/packages/pyright-internal/src/tests/checker.test.ts
+++ b/packages/pyright-internal/src/tests/checker.test.ts
@@ -721,3 +721,8 @@ test('Deprecated8', () => {
     const analysisResults2 = TestUtils.typeAnalyzeSampleFiles(['deprecated8.py'], configOptions);
     TestUtils.validateResults(analysisResults2, 4);
 });
+
+test('TypeNarrowingContainer1', () => {
+    const analysisResults = TestUtils.typeAnalyzeSampleFiles(['typeNarrowingContainer1.py']);
+    TestUtils.validateResults(analysisResults, 0);
+});
diff --git a/packages/pyright-internal/src/tests/samples/typeNarrowingContainer1.py b/packages/pyright-internal/src/tests/samples/typeNarrowingContainer1.py
new file mode 100644
index 000000000000..a1961ffcadfb
--- /dev/null
+++ b/packages/pyright-internal/src/tests/samples/typeNarrowingContainer1.py
@@ -0,0 +1,38 @@
+# This sample tests negative type narrowing for tuple membership checks (in / not in)
+# containing instantiable class objects (type[T]).
+
+from typing import final
+from typing_extensions import assert_type
+
+@final
+class FinalClassA: pass
+
+@final
+class FinalClassB: pass
+
+class ClassC: pass
+
+class NonFinalClassA: pass
+class SubA(NonFinalClassA): pass
+
+
+def test_in_final_class_tuple(x: type[FinalClassA] | type[FinalClassB] | type[ClassC]):
+    if x in (FinalClassA, FinalClassB):
+        assert_type(x, type[FinalClassA] | type[FinalClassB])
+    else:
+        assert_type(x, type[ClassC])
+
+def test_not_in_final_class_tuple(x: type[FinalClassA] | type[FinalClassB] | type[ClassC]):
+    if x not in (FinalClassA, FinalClassB):
+        assert_type(x, type[ClassC])
+    else:
+        assert_type(x, type[FinalClassA] | type[FinalClassB])
+
+def test_not_in_non_final_class_tuple(x: type[NonFinalClassA] | type[ClassC]):
+    if x not in (NonFinalClassA,):
+        # SubA is a subclass of NonFinalClassA. At runtime, SubA in (NonFinalClassA,)
+        # evaluates to False, so SubA reaches this negative branch. Therefore,
+        # type[NonFinalClassA] must not be eliminated when NonFinalClassA is not final.
+        assert_type(x, type[NonFinalClassA] | type[ClassC])
+    else:
+        assert_type(x, type[NonFinalClassA])